REpressive chromatin lncRNA

Characterization of repressive chromatin associated lncRNAs

Pathways regulated by repressive chromatin associated lncRNA MEG3 and EZH2 (PRC2 catalytic subunit)

MEG3 forming RNA-DNA triplex structure and recruits PRC2 to the distal regulatory elements to control expression of TGF-beta pathway genes

Note: Above findings are published in Nature Communications, Issue 6 (Mondal T et al, 2015). Only computational analysis results contributed by me is included in above summary. For complete research, please have a look at this original article.